# To IV or Not to IV: The Science Behind Intravenous Vitamin Therapy

**Authors:** Abdulrahman Alangari

PMC · DOI: 10.7759/cureus.86527 · 2025-06-22

## TL;DR

This paper explains the science behind IV vitamin therapy, comparing its benefits and drawbacks to oral supplementation.

## Contribution

The paper offers a comprehensive overview of IV vitamin therapy's physiological and clinical aspects.

## Key findings

- IV therapy provides higher bioavailability and therapeutic dosages compared to oral intake.
- It is particularly beneficial for individuals with malabsorption issues and chronic illnesses.
- Oral supplementation remains a practical option for routine nutrient intake.

## Abstract

Intravenous (IV) vitamin therapy has become an increasingly popular method for delivering essential micronutrients directly into the bloodstream, bypassing the gastrointestinal tract. This method offers enhanced bioavailability, higher therapeutic dosages, and targeted nutrient replenishment, making it particularly effective for individuals with malabsorption issues and chronic illnesses and those seeking optimal health benefits. In contrast, oral supplementation remains a convenient and practical option for routine vitamin and mineral intake. This article provides an overview of the physiological advantages and disadvantages of IV vitamin therapy, its clinical applications, and the scientific evidence supporting its efficacy.

## Full-text entities

- **Diseases:** malabsorption (MESH:D008286)

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Source: https://tomesphere.com/paper/PMC12182718