# Vaccine-Induced Lichen Planus in a 12-Year-Old Patient: A Rare Pediatric Case

**Authors:** Sara Nejjari, Inas Chikhaoui, Ghita Basri, Soumiya Chiheb

PMC · DOI: 10.7759/cureus.84521 · Cureus · 2025-05-21

## TL;DR

A 12-year-old boy developed lichen planus, a skin condition, after a tetanus vaccine, highlighting the rare immune reaction and the role of dermoscopy in diagnosis.

## Contribution

This case is one of the few reports of vaccine-induced lichen planus in a pediatric patient, emphasizing its recognition and diagnostic utility of dermoscopy.

## Key findings

- A 12-year-old male developed lichen planus two weeks after a tetanus vaccine.
- Dermoscopy aided in the non-invasive diagnosis of lichen planus in this case.
- Vaccine-induced lichen planus is rare but should be considered in pediatric patients with new skin lesions post-vaccination.

## Abstract

We report a rare case of vaccine-induced lichen planus (LP) in a 12-year-old male patient who developed generalized pruritic, violaceous, flat-topped papules and plaques two weeks after receiving a tetanus vaccine following a puncture wound. Clinical evaluation, dermoscopic examination showing Wickham striae and follicular hyperkeratosis, and histopathology confirmed the diagnosis. Vaccine-induced LP remains an uncommon but possible immune-mediated adverse reaction. Dermoscopy proved valuable for non-invasive diagnosis, aiding in distinguishing LP from other dermatologic conditions. This case emphasizes the importance of considering vaccine-induced LP in pediatric patients presenting with new-onset lesions post-vaccination and highlights the role of dermoscopy in early recognition and management.

## Linked entities

- **Diseases:** lichen planus (MONDO:0006572)

## Full-text entities

- **Diseases:** Wickham striae (MESH:D057896), hyperkeratosis (MESH:D017488), LP (MESH:D008010), tetanus (MESH:D013746)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12182224/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12182224/full.md

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Source: https://tomesphere.com/paper/PMC12182224