# Draft genome sequence of Flavobacterium aquidurense strain, isolated from untreated wastewater

**Authors:** Alexander D. H. Kingdon, Kara D’Arcy, Anya Breen, Claudia McKeown, Ellie Allman, Priyanka Sharma, Amy McLeman, Adam P. Roberts

PMC · DOI: 10.1099/acmi.0.000976.v3 · Access Microbiology · 2025-06-20

## TL;DR

Scientists sequenced the genome of a Flavobacterium aquidurense strain from wastewater, revealing genes for pigments and antibiotic resistance.

## Contribution

The study provides a new draft genome with insights into pigment biosynthesis and antimicrobial resistance in Flavobacterium.

## Key findings

- The genome contains genes for flexirubin and β-carotene production.
- A putative novel β-lactone biosynthetic gene cluster was identified.
- A β-lactamase gene and multiple copies of an IS3 family insertion sequence were found.

## Abstract

Here, we report the draft 5.8 Mb genome sequence of a Flavobacterium aquidurense isolate from untreated wastewater in Liverpool, United Kingdom. The reported isolate has the potential to produce both flexirubin and β-carotene pigments, and contains an additional biosynthetic gene cluster for a putative novel β-lactone. The genome also contains a gene for a putative β-lactamase blaJOHN-1 analogue, and there are multiple copies of a putative novel insertion sequence of the IS3 family. This genome adds to a growing resource of Flavobacterium spp. sequencing data which can be utilized to investigate microbial pigment production, antimicrobial resistance genes and mobile genetic elements within this genus.

## Linked entities

- **Chemicals:** flexirubin (PubChem CID 6450309), β-carotene (PubChem CID 573)
- **Species:** Flavobacterium aquidurense (taxon 362413), Mus musculus (taxon 10090)

## Full-text entities

- **Chemicals:** flexirubin (MESH:C017313), beta-lactone (-), beta-carotene (MESH:D019207)
- **Species:** Flavobacterium aquidurense (species) [taxon 362413]

## Full text

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## Figures

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12181623/full.md

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Source: https://tomesphere.com/paper/PMC12181623