# Cerebral Lymphangioma: A Clinical Case History

**Authors:** Fadwa Fliyou, Sidi Mamoun Louraoui, Youssef Ouboukhlik, Mounir Rghioui, Abdessamad El Azhari, Faycal Moufid

PMC · DOI: 10.7759/cureus.86455 · Cureus · 2025-06-20

## TL;DR

A rare case of cerebral lymphangioma in an adult is reported, highlighting its diagnostic challenges and successful treatment through surgery.

## Contribution

This is one of the few documented cases of cerebral lymphangioma in an adult, offering insights into its clinical presentation and management.

## Key findings

- The patient showed marked improvement in headache and motor strength after surgical resection.
- MRI findings initially suggested a cystic meningioma, but histopathology confirmed lymphangioma.
- Complete surgical resection led to favorable clinical outcomes in this case.

## Abstract

Cerebral lymphangioma is an extremely rare entity, especially in adults. We report the case of a 38-year-old male who presented with diabetic ketoacidosis (fasting glucose: 4.65 g/L; glycated hemoglobin (HbA1c): 9.5%; urinary ketones and glucose: 4+ (highly positive)), severe holocranial headache, left hemiparesis, and agitation. MRI revealed a 58×46.5 mm right parietal extra-axial lesion with cystic and hemorrhagic components, initially suggestive of a cystic meningioma. Gross total surgical resection was performed following metabolic stabilization. Histopathology confirmed the diagnosis of lymphangioma. Postoperatively, the patient experienced a marked reduction in headache intensity (from 8/10 to 2/10 on the visual analog scale) and improvement in motor strength.

This case illustrates the diagnostic challenge posed by cerebral lymphangiomas, which may closely mimic other cystic extra-axial lesions on imaging, particularly hemorrhagic meningiomas. It also demonstrates that complete surgical resection can result in favorable clinical outcomes. To our knowledge, this is one of the very few documented cases of cerebral lymphangioma in an adult, underscoring the need for increased awareness and further case reports to guide diagnosis and management.

## Linked entities

- **Chemicals:** glucose (PubChem CID 5793)
- **Diseases:** diabetic ketoacidosis (MONDO:0012819), lymphangioma (MONDO:0002013)

## Full-text entities

- **Diseases:** diabetic ketoacidosis (MESH:D016883), hemiparesis (MESH:D010291), hemorrhagic (MESH:D006470), Cerebral Lymphangioma (MESH:D008202), headache (MESH:D006261), cystic meningioma (MESH:D018297), agitation (MESH:D011595)
- **Chemicals:** ketones (MESH:D007659), glucose (MESH:D005947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12180949/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12180949/full.md

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Source: https://tomesphere.com/paper/PMC12180949