# Right-sided descending colon with necrotizing enterocolitis: a rare case report

**Authors:** Ting Wang, Shunlin Xia, Mengxu Liu, Youcheng Zhang, Yu Liu

PMC · DOI: 10.3389/fped.2025.1557672 · 2025-06-06

## TL;DR

This case report describes a rare anatomical variation of the descending colon in a newborn with necrotizing enterocolitis, highlighting the importance of recognizing such variations for surgical safety.

## Contribution

The paper presents a rare case of right-sided descending colon with necrotizing enterocolitis, emphasizing its clinical and surgical implications.

## Key findings

- The descending colon was fixed to the posterior abdominal wall and extended abnormally to the right side.
- The infant developed necrotizing enterocolitis with extensive mucosal ulceration and transmural necrosis.
- A total colectomy with end ileostomy was performed, and the newborn recovered well postoperatively.

## Abstract

Anatomical variations of the colon are commonly reported, with the majority involving the right colon. However, anomalies affecting the left colon, particularly the descending colon, are rarely described in the literature.

We reviewed the clinical records of right-sided descending colon with necrotizing enterocolitis involvement at our hospital, detailing the patients’ onset, imaging studies, complications, and treatment.

A newborn experienced repeated vomiting. Upper and lower gastrointestinal imaging revealed gastroesophageal reflux, the right-sided descending and sigmoid colon. Two weeks later, the infant developed NEC, and after failure of conservative treatment, surgical intervention was performed. We found that the descending colon was fixed to the posterior abdominal wall, extending from the splenic flexure toward the right side and crossing the midline. The entire colon is dilated with thickened walls. Extensive mucosal ulceration is present, accompanied by transmural necrosis. Postoperative pathology reveals significant infiltration of inflammatory cells. The most severely affected regions were the descending and sigmoid colon. Consequently, a total colectomy with end ileostomy was performed, while the distal part of sigmoid colon was preserved. Postoperatively, the newborn recovered well.

This case may help raise awareness among surgeons regarding the variability in the position of the descending colon. It is essential to consider such anatomical variations before performing related procedures in this area, to enhance surgical safety and avoid colonic injury.

## Linked entities

- **Diseases:** necrotizing enterocolitis (MONDO:0004639), gastroesophageal reflux (MONDO:0007186)

## Full-text entities

- **Diseases:** colonic injury (MESH:D003108), inflammatory (MESH:D007249), necrotizing enterocolitis (MESH:D020345), gastroesophageal reflux (MESH:D005764), necrosis (MESH:D009336), vomiting (MESH:D014839)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12179201/full.md

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Source: https://tomesphere.com/paper/PMC12179201