# Endovascular management of primary long-segment inferior vena cava occlusion: treatment strategies and clinical outcomes

**Authors:** Jianjun Jiang, Mingli Li, Guangzhen Li, Yang Liu, Qingbo Su

PMC · DOI: 10.3389/fphar.2025.1512157 · 2025-06-06

## TL;DR

This study explores endovascular treatments for a rare condition involving blockage of the inferior vena cava, showing improved patient outcomes.

## Contribution

The study provides clinical evidence supporting endovascular therapy as an effective treatment for primary long-segment IVC occlusion.

## Key findings

- Endovascular treatment achieved favorable patency rates and symptom improvement in patients with IVC occlusion.
- Angioplasty and stent placement were effective in restoring blood flow without major complications.
- Long-term anticoagulant prophylaxis is recommended to prevent venous thrombosis after treatment.

## Abstract

Primary long-segment occlusion of the inferior vena cava (IVC) is a rare condition with diverse clinical presentations. The optimal management approach for this condition remains uncertain, warranting further investigation into endovascular treatment methods.

A retrospective study conducted at Qilu Hospital of Shandong University from 2012 to 2018 assessed 16 patients with primary long-segment IVC occlusion. Patients underwent comprehensive imaging evaluations and received endovascular interventions such as angioplasty, stent placement, and online blood flow restoration. Additionally, a literature review was performed to analyze current practices in managing IVC occlusion.

Endovascular treatment was completed in all patients, with favorable primary and secondary patency rates during follow-up. Clinical symptoms significantly improved post-treatment, and the majority of patients achieved IVC patency without major complications. The study showcased the efficacy of angioplasty and stent placement in managing primary IVC occlusion.

Endovascular therapy is a safe and effective approach for tackling long-segment IVC occlusion, leading to improved patient outcomes. Long-term anticoagulant prophylaxis is advised to mitigate the risk of venous thrombosis in these patients. This study contributes valuable insights for guiding clinical practice in treating primary IVC occlusion.

## Full-text entities

- **Diseases:** IVC occlusion (MESH:C563013), venous thrombosis (MESH:D020246)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12179148/full.md

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Source: https://tomesphere.com/paper/PMC12179148