# Successful Percutaneous Closure of Post-myocardial Infarction (MI) Ventricular Septal Defect (VSD) Using the Trans-septal Approach: A Case Report

**Authors:** Monika Karki, Pramod Bhattarai, Yash Raval, Arnoux Blanchard, Kathir Subramanian

PMC · DOI: 10.7759/cureus.84476 · 2025-05-20

## TL;DR

This case report describes a successful non-surgical repair of a heart defect in an elderly patient after a heart attack.

## Contribution

Demonstrates the feasibility and safety of percutaneous VSD closure via a trans-septal approach in high-risk patients.

## Key findings

- Percutaneous closure was successfully performed in an 80-year-old male with post-MI VSD.
- The trans-septal approach was safe and resulted in a favorable clinical outcome.
- This case highlights a viable alternative to surgery for high-risk patients.

## Abstract

Ventricular septal defect (VSD) following myocardial infarction (MI) is a rare but life-threatening complication associated with high morbidity and mortality. While surgical repair remains the standard of care, its high mortality risk has prompted the exploration of percutaneous alternatives, especially in patients with elevated surgical risk. This case report describes the successful percutaneous closure of a post-MI VSD via a trans-septal approach in an 80-year-old male, highlighting its feasibility, safety, and favorable clinical outcome in a high-risk patient.

## Linked entities

- **Diseases:** myocardial infarction (MONDO:0005068), ventricular septal defect (MONDO:0002070)

## Full-text entities

- **Diseases:** VSD (MESH:D006345), MI (MESH:D009203)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12178273/full.md

---
Source: https://tomesphere.com/paper/PMC12178273