# Finite-time analysis of epidemic reaction-diffusion models: Stability, synchronization, and numerical insights

**Authors:** Iqbal Batiha, Nidal Anakira, Issam Bendib, Adel Ouannas, Amel Hioual, Irianto Irianto, Ala Amourah

PMC · DOI: 10.1371/journal.pone.0321132 · PLOS One · 2025-05-27

## TL;DR

This paper introduces a new method to study how diseases spread in space and time, using mathematical models to better understand and control outbreaks.

## Contribution

The paper introduces a novel framework for finite-time stability and synchronization in reaction-diffusion systems, particularly for epidemiological modeling.

## Key findings

- The proposed framework effectively analyzes transient dynamics in spatially extended systems.
- MATLAB simulations confirm the practical applicability of the control schemes in disease transmission modeling.
- The study highlights the impact of diffusion rates and mortality on system behavior.

## Abstract

This study presents an innovative approach to analyzing finite-time stability (FTS) and synchronization (FTSYN) in integer-order reaction-diffusion systems (RDs), particularly in the context of epidemiological modeling. By integrating Gronwall’s inequality, Lyapunov functionals (LFs), and linear control strategies, a comprehensive framework is developed to address transient dynamics within finite time frames. The proposed methodology advances the theoretical understanding of FTS and FTSYN by addressing the relatively unexplored dynamics of spatially extended systems. MATLAB simulations validate the theoretical findings, demonstrating the effectiveness of the control schemes and their practical applicability in modeling real-world disease transmission. Integrating spatial diffusion and disease dynamics provides critical insights into the influence of parameters such as diffusion rates and mortality on system behavior. This work contributes a robust framework for enhancing the analysis and management of nonlinear systems, with significant implications for epidemiology and other fields requiring rapid convergence and synchronization.

## Full-text entities

- **Chemicals:** FTSYN (-)

## Full text

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## Figures

22 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12178015/full.md

## References

46 references — full list in the complete paper: https://tomesphere.com/paper/PMC12178015/full.md

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Source: https://tomesphere.com/paper/PMC12178015