# Neuro-Behçet’s Syndrome: A Case Report

**Authors:** David I LeRoy, Elaine Ognjanovski, Silvia Menkes, Kristen Kenny, Cassie Konja

PMC · DOI: 10.7759/cureus.84421 · Cureus · 2025-05-19

## TL;DR

This case report describes a rare neurological complication of Behçet's syndrome and emphasizes the need for a multidisciplinary approach in managing such complex cases.

## Contribution

The paper presents a detailed case of Neuro-Behçet’s Syndrome and highlights the lack of clinical trials on its treatment.

## Key findings

- Neuro-Behçet’s Syndrome is rare and presents with diverse neurological symptoms.
- Diagnosis is challenging due to varied clinical manifestations.
- Multidisciplinary care is essential for managing complications in NBS patients.

## Abstract

Behçet's syndrome is a systemic vasculitis characterized by recurrent oral and genital ulcers, uveitis, and often involvement of multiple organ systems. Neurological involvement is a rare complication of Behçet's syndrome and is associated with significant morbidity and mortality. Neuro-Behçet's syndrome (NBS) is a combination of neurologic manifestations in a patient with Behçet's syndrome, including movement disorders, myelopathic syndrome, intracranial hypertension, and a multiple sclerosis-like presentation. Diagnosis of NBS can be challenging due to the wide range of clinical presentations. Although previous research has aided in advancing the understanding of the pathophysiology and treatment of systemic Behçet's syndrome, there is a lack of randomized controlled studies involving the treatment of NBS. This case report describes a patient with NBS who experienced a complex hospital course, highlighting the need for a multidisciplinary team approach to address various complications.

## Linked entities

- **Diseases:** Behçet's syndrome (MONDO:0007191), uveitis (MONDO:0020283), intracranial hypertension (MONDO:0006810)

## Full-text entities

- **Diseases:** myelopathic syndrome (MESH:D009134), movement disorders (MESH:D009069), oral (MESH:D020820), ulcers (MESH:D014456), uveitis (MESH:D014605), Behçet's syndrome (MESH:D001528), systemic vasculitis (MESH:D056647), Neurological involvement (MESH:C538190), intracranial hypertension (MESH:D019586), NBS (MESH:C536203), multiple sclerosis (MESH:D009103)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12177433/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12177433/full.md

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Source: https://tomesphere.com/paper/PMC12177433