# Comparability, acceptability and longitudinal adherence with digital emPHasis-10 in pulmonary arterial hypertension

**Authors:** Joseph Newman, Frances Varian, Felicity Hitchcock, Rebecca Burney, Gregg Harry Rawlings, John Harrington, Ze Ming Goh, Jenna Ablott, David G. Kiely, Iain Armstrong, A.A. Roger Thompson, Jill Carlton, Elin Haf Davies, Alexander Rothman, Mark Toshner

PMC · DOI: 10.1183/13993003.00198-2025 · The European Respiratory Journal · 2025-06-19

## TL;DR

This study introduces a digital version of the emPHasis-10 tool for pulmonary hypertension patients, showing it is valid, well-accepted, and has good long-term adherence.

## Contribution

The paper introduces a digital version of the emPHasis-10 PROM for pulmonary hypertension patients, demonstrating its validity and acceptability.

## Key findings

- Digital emPHasis-10 showed high acceptability among patients.
- Longer-term adherence to the digital tool was observed.
- The digital version maintained the validity of the original paper-based emPHasis-10.

## Abstract

Pulmonary hypertension (PH) affects 1% of the global population and significantly impacts health-related quality of life (HRQoL) [1, 2]. Patient-reported outcome measures (PROMs) are standardised tools used in clinical practice and research to assess health outcomes from the patient's perspective. Routine measurement of HRQoL is supported by clinical guidelines, which recommend disease-specific PROMs [1]. EmPHasis-10 is a widely used 10-item PROM developed for patients in any World Health Organization (WHO) PH group [2, 3]. Available in numerous languages, it has strengths in both its psychometric properties and feasibility [2, 4]. However, it is currently only available in a paper-based format.

Digital emPHasis-10 is an app-based patient-reported outcome measure for trial or clinical use by patients with pulmonary hypertension. This letter demonstrates this novel tool's validity, longer-term adherence and high acceptability scores from patients.
https://bit.ly/4lZiXkE

## Linked entities

- **Diseases:** pulmonary hypertension (MONDO:0005149)

## Full-text entities

- **Diseases:** pulmonary hypertension (MESH:D006976), pulmonary arterial hypertension (MESH:D000081029)
- **Chemicals:** emPHasis-10 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12177334/full.md

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Source: https://tomesphere.com/paper/PMC12177334