# Extra-gastrointestinal Stromal Tumor of the Urinary Bladder: A Report of a Rare Case and Literature Review

**Authors:** Swapnil S Kushwaha, Abhilash Goyal, Shikha Goja

PMC · DOI: 10.7759/cureus.84435 · Cureus · 2025-05-19

## TL;DR

A rare case of a bladder tumor similar to gastrointestinal stromal tumors is reported, emphasizing the need for proper diagnosis and treatment.

## Contribution

This paper presents a rare case of eGIST in the urinary bladder and emphasizes its clinical management.

## Key findings

- A 40-year-old man was diagnosed with eGIST of the urinary bladder after cystoscopy and transurethral resection.
- The patient underwent successful partial cystectomy and showed no recurrence after 28 months.
- The case highlights the importance of recognizing bladder eGIST for appropriate management.

## Abstract

Extra-gastrointestinal stromal tumors (eGISTs) are rare tumors that occur outside the gastrointestinal tract but share similar histological and molecular characteristics as GISTs. This report highlights an exceptionally rare case of eGISTs in the urinary bladder of a 40-year-old man who presented with painless gross total hematuria. Computed tomography (CT) revealed a solitary bladder mass, approximately 3 × 3 cm over the anterior wall, with extravesical extension into the urachal remnants. He was diagnosed with eGIST of the urinary bladder based on histopathology and immunohistochemistry after cystoscopy and transurethral resection. The patient underwent open partial cystectomy and excision of the urachus, with an uneventful recovery and no recurrence at 28 months follow-up. This case report underscores the importance of recognizing and appropriately managing bladder eGISTs.

## Full-text entities

- **Diseases:** tumors (MESH:D009369), Extra-gastrointestinal Stromal Tumor (MESH:D046152), hematuria (MESH:D006417)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12177211/full.md

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Source: https://tomesphere.com/paper/PMC12177211