# The research beamlines at the Dresden proton therapy facility: available infrastructure and experimental capabilities

## TL;DR

The Dresden proton therapy facility offers two beamlines for research, enabling experiments on proton therapy techniques and biological effects.

## Contribution

The paper introduces two distinct beamlines with unique parameters for translational research in proton therapy.

## Key findings

- One beamline delivers scanned beams with quasi-clinical parameters, while the other provides continuous and pulsed pencil beams.
- The facility supports parallel beam operation with clinical treatment, allowing weekday irradiation experiments.
- The infrastructure enables large-scale experiments and collaborations for developing new proton therapy approaches.

## Abstract

The proton therapy facility in Dresden, Germany, has one treatment room equipped with a rotating gantry where patients are treated and an experimental room equipped with two horizontal beamlines for translational research. The present work describes the technical characteristics and provides measured beam data of these two complementary beamlines, one delivering scanned beams with quasi-clinical parameters and the other one stationary continuous and pulsed pencil beams with parameters exceeding the clinically used range. Features of the facility are the large scale of the experimental room enabling the development and installation of large devices and the parallel beam operation with the clinical room allowing irradiation experiments on weekdays and during daytime. An overview of past and ongoing physics and biology experiments performed at the facility by internal and external researchers from academia and industry is given, demonstrating its versatile experimental capabilities. This includes the development of novel proton therapy approaches and technology as well as elaborate in-vitro and in-vivo small animal experiments for which the necessary infrastructure is available in the same building.