# Mortality and admissions for cerebrovascular and cardiovascular diseases after the Accumoli-Amatrice 2016 earthquake

**Authors:** Chiara Cadeddu, Mario Cesare Nurchis, Carolina Castagna, Martina Sapienza, Rosaria Messina, Stefano Marchetti, Walter Ricciardi, Aldo Rosano, Francesco Branda, Francesco Branda, Francesco Branda, Emma Campbell, Francesco Branda, Francesco Branda

PMC · DOI: 10.1371/journal.pone.0326242 · PLOS One · 2025-06-18

## TL;DR

This study found that heart-related deaths and hospital admissions increased after the 2016 Accumoli-Amatrice earthquake, highlighting the health risks of natural disasters.

## Contribution

The study provides new evidence linking earthquakes to increased cardiovascular mortality and admissions.

## Key findings

- Mortality from acute myocardial infarction increased by 1.7 cases per 10,000 after the earthquake.
- Hospital admissions for acute myocardial infarction also significantly increased in the affected area.

## Abstract

The aim of this study is to evaluate if the mortality and hospital admissions for cerebrovascular and cardiovascular diseases (CCVDs), with a specific focus on acute myocardial infarction (AMI), significantly increased within 12 months after the 2016 Accumoli-Amatrice earthquake in the 17 most hit municipalities.

A diff-in-diff regression model was applied to the annual occurrences to assess the differences in the mortality and hospitalization for selected CCVDs before and after the Earthquake in the area most hit by the earthquake compared to a surrounding area. A focus analysis on acute myocardial infarction (AMI) was performed.

The analysis of mortality showed a significant increase in the death rate for AMI in the year immediately following the earthquake with +1.7 cases per 10,000 (95% CI: 1.53–1.87). A significantly increased number of hospital admissions and deaths for AMI was also noticed.

Evaluating the epidemiology of CCVDs events related to natural disasters, might contribute to provide information for the population dealing with future events and can be used to improve preparedness in rescue and life-saving medical interventions during and after the earthquake.

## Linked entities

- **Diseases:** acute myocardial infarction (MONDO:0004781)

## Full-text entities

- **Diseases:** AMI (MESH:D009203), CCVDs (MESH:D002318), death (MESH:D003643)

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12176150/full.md

## References

48 references — full list in the complete paper: https://tomesphere.com/paper/PMC12176150/full.md

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Source: https://tomesphere.com/paper/PMC12176150