# Assessment of the ability to predict complications of the Risk Factor Scale for Pre-eclampsia Complications and the fullPIERS scale in pregnant women in a Hospital in Lima, Peru

## TL;DR

This study compared two risk scales for predicting preeclampsia complications in pregnant women in Peru, finding both useful but with locally adjusted cutoff points.

## Contribution

The study evaluates and compares the performance of RFSPC and fullPIERS scales in a Peruvian hospital setting, identifying optimal local cutoff points.

## Key findings

- The RFSPC scale had a sensitivity of 71%, specificity of 73%, and AUC of 0.722 with a cutoff of 3 points.
- The fullPIERS scale showed higher performance with 76% sensitivity, 84% specificity, and AUC of 0.804 at a cutoff of 0.75%.
- Both scales can identify at-risk pregnant women using locally adjusted cutoff points.

## Abstract

To evaluate the ability of the Risk Factor Scale for Preeclampsia Complications (RFSPC) and the fullPIERS (Pre-eclampsia Integrated Estimate of RiSk) scale to predict complications of preeclampsia in pregnant women diagnosed with preeclampsia who were admitted to the obstetrics and gynecology department of a referral hospital, from October 2021 to December 2022.

This was a retrospective cohort design study. Data was collected from the medical records of patients diagnosed with preeclampsia, and both scales (RFSPC and fullPIERS) were applied. With these results, the sensitivity, specificity and the area under the ROC curve (AUC) were obtained by taking different cut-off points. The best score was selected as the one with the highest AUC. The differences between the scales were explored by comparing their AUCs.

We included 367 pregnant women. The RFSPC had a sensitivity of 71%, a specificity of 73% and an AUC of 0.722 with a cutoff point of 3 points. Whereas the fullPIERS scale showed 76%, 84% and 0.804 respectively with a cutoff point of 0.75%.

Both scales can be useful for identifying pregnant women at risk of complications with cutoff points different from those defined internationally.

Evaluar las capacidades para predecir complicaciones de preeclampsia de la Escala de Factores de Riesgo para Complicaciones de Preeclampsia (EFRCP) y la escala fullPIERS (Pre-eclampsia Integrated Estimate of RiSk) en gestantes con diagnóstico de preeclampsia que ingresan al servicio de gineco-obstetricia de un hospital de referencia, desde octubre del 2021 a diciembre del 2022.

Estudio de diseño de cohorte retrospectivo, se recolectaron los datos de historias clínicas de pacientes diagnosticadas con preeclampsia y se aplicó ambas escalas (EFRCP y fullPIERS). Con estos resultados se halló la sensibilidad, especificidad y el área bajo la curva ROC (AUC) tomando diferentes puntos de corte. Se seleccionó como mejor puntaje aquel con una mayor AUC. Se exploró las diferencias entre las escalas comparando sus AUC.

Se incluyeron a 367 gestantes. La EFRCP presentó 71% de sensibilidad, 73% de especificidad y AUC de 0,722 con un punto de corte de 3 puntos. Mientras que en la escala de fullPIERS obtuvimos 76%, 84% y 0,804 respectivamente con el punto de corte de 0,75%.

Ambas escalas pueden ser de utilidad para identificar gestantes en riesgo de complicaciones con puntos de corte diferentes a los definidos internacionalmente.