# A fast and easy-to-perform noninvasive Muller’s muscle sublimation technique using plasma technology for treatment of mild-to-moderate ptosis: a case report

**Authors:** Nasrin Raffati

PMC · DOI: 10.1186/s13256-025-05330-y · Journal of Medical Case Reports · 2025-06-17

## TL;DR

A new noninvasive technique using plasma technology to treat mild-to-moderate ptosis shows promising results in a case series of six women.

## Contribution

The study introduces a plasma-based sublimation method as a less invasive alternative to traditional ptosis surgery.

## Key findings

- Plasma technology improved margin reflex distance from 1.58 mm to 3.66 mm after six months.
- The conjunctivo-Muller sublimation technique was well-tolerated with no major complications reported.

## Abstract

Currently, most surgeons favor Muller’s muscle conjunctival resection as a treatment for mild-to-moderate ptosis, as this method is associated with fewer post-surgical complications.

This case series of six Iranian women aged between 15 and 65 (mean 43) years with mild-to-moderate ptosis treated at Negah Eye Hospital used a plasma scalpel (PLEXR™) for conjunctivo-Muller sublimation. A 1–4 area management strategy was applied, and margin reflex distance 1 measurements showed improvement from 1.58 mm pre-treatment to 3.66 mm after 6 months.

Seemingly, applying plasma technology to treat mild-to-moderate ptosis via conjunctivo-Muller muscle sublimation might be a promising alternative to more invasive surgical methods.

## Linked entities

- **Diseases:** ptosis (MONDO:0000728)

## Full-text entities

- **Diseases:** ptosis (MESH:C564553)
- **Chemicals:** PLEXR (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12175309