# Gene model for the ortholog of lin-28 in Drosophila simulans

**Authors:** Megan E. Lawson, Hannan Saeed, Cassie Tran, Simran Chhina, Jack A. Vincent, Brian Schwartz, Kellie S. Agrimson, Christopher E. Ellison, Chinmay P. Rele, Laura K Reed

PMC · DOI: 10.17912/micropub.biology.000963 · microPublication Biology · 2025-06-04

## TL;DR

This paper presents a gene model for the lin-28 ortholog in Drosophila simulans as part of a study on the evolution of the IIS pathway.

## Contribution

The paper provides a new gene model for lin-28 in Drosophila simulans using a standardized annotation protocol.

## Key findings

- A gene model for the lin-28 ortholog was identified in the Drosophila simulans genome.
- The study contributes to a dataset for analyzing the evolution of the IIS pathway in Drosophila.
- The annotation was performed using the Genomics Education Partnership protocol for undergraduate research.

## Abstract

Gene model for the ortholog of

lin-28

(

lin-28

) in the May 2017 (Princeton ASM75419v2/DsimGB2) Genome Assembly (GenBank Accession:
GCA_000754195.3
) of
Drosophila simulans
. This ortholog was characterized as part of a developing dataset to study the evolution of the Insulin/insulin-like growth factor signaling pathway (IIS) across the genus
Drosophila
using the Genomics Education Partnership gene annotation protocol for Course-based Undergraduate Research Experiences.

## Linked entities

- **Genes:** LIN28A (lin-28 RNA binding posttranscriptional regulator A) [NCBI Gene 79727]
- **Species:** Drosophila simulans (taxon 7240), Drosophila (taxon 7215)

## Full-text entities

- **Species:** Drosophila simulans (species) [taxon 7240]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12174996/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12174996/full.md

## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12174996/full.md

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Source: https://tomesphere.com/paper/PMC12174996