# A Diagnostically Challenging Case of Typical Hemolytic Uremic Syndrome Successfully Treated With Eculizumab Therapy

## TL;DR

A severe case of typical hemolytic uremic syndrome was successfully treated with eculizumab despite diagnostic challenges.

## Contribution

Demonstrates successful treatment of a complex typical HUS case using eculizumab.

## Key findings

- Eculizumab therapy successfully treated a severe case of typical HUS.
- Multidisciplinary care was essential in managing complications.
- Diagnostic challenges were overcome through careful clinical evaluation.

## Abstract

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy that induces microvesicular injury and occlusion and often results in acute renal failure. Atypical HUS is life-threatening and often progresses to end-stage renal disease (ESRD). However, distinguishing between typical and atypical HUS can be challenging due to comorbid conditions and/or laboratory delays. We present a severe case of typical HUS involving a series of complications requiring multidisciplinary care, successfully treated with eculizumab therapy.