# Mixed drug overdose involving clonazepam, alprazolam, and olanzapine in a 72-year-old male with Parkinson’s disease: a case report

## TL;DR

An elderly man with Parkinson's disease overdosed on multiple drugs and recovered with supportive care.

## Contribution

A detailed case report of a mixed drug overdose in an elderly Parkinson’s patient, emphasizing treatment challenges and recovery.

## Key findings

- The patient ingested over 30 clonazepam tablets along with alprazolam and olanzapine.
- Supportive care and renal replacement therapy were critical in the patient's recovery.
- The case underscores the difficulty in managing drug overdoses with long-half-life medications in elderly patients.

## Abstract

This case report discusses a 72-year-old male patient with Parkinson’s disease, depression, and somatization disorder, presenting to the emergency department after a suspected overdose of clonazepam. The patient was discovered unconscious approximately 2.5 h after ingestion of over 30 tablets of clonazepam, in combination with an overdose of alprazolam and olanzapine. Despite initial challenges with gastric lavage, subsequent treatment involved supportive care, management of complications such as pneumonia, and renal replacement therapy, ultimately leading to recovery. This case highlights the complexities of managing overdoses, particularly those involving drugs with long half-lives, and highlights the challenges of treating elderly patients and the importance of supportive care in recovery.