# The role of facet joint degeneration in the treatment success of transforaminal epidural steroid injection: a retrospective clinical study

**Authors:** Merve Sekizkardes Tutuncu, Savas Sencan, Canan Bilekyigit Kurt, Serdar Kokar, Osman Hakan Gunduz

PMC · DOI: 10.1007/s00256-025-04868-8 · 2025-01-22

## TL;DR

This study shows that higher facet joint degeneration reduces the effectiveness of a common back pain treatment called transforaminal epidural steroid injection.

## Contribution

The study identifies facet joint degeneration as a novel predictor of treatment success in transforaminal epidural steroid injections.

## Key findings

- Patients with high-grade facet joint degeneration had higher pain scores 3 weeks after treatment.
- Treatment success was significantly lower in patients with high-grade facet joint degeneration.
- Facet joint degeneration negatively affects the long-term outcomes of TFESI.

## Abstract

Transforaminal epidural steroid injection (TFESI) is highly effective in alleviating radicular back pain. While predictive factors for TFESI treatment outcomes have been previously studied, there is a lack of data on the relationship between facet joint degeneration and TFESI efficacy. This study is aimed at studying the impact of facet joint degeneration on TFESI treatment outcomes for unilateral radicular pain.

A retrospective analysis was conducted on patients with unilateral radicular pain who underwent lumbosacral TFESI. Pain severity was assessed using the Numerical Rating Scale (NRS) at baseline, 1 h post-procedure, and 3 weeks post-procedure. Degree of facet joint degeneration was evaluated via MRI. Patients were categorized into two groups: low-grade facet joint degeneration group (group 1) and high-grade facet joint degeneration group (group 2).

A total of 147 patients were included in the study. NRS scores were significantly higher in group 2 compared to group 1 at the 3rd week follow-up. Treatment success, defined as a ≥ 50% reduction in NRS scores, was also significantly higher in group 1.

Facet joint degeneration adversely impacts the treatment success of TFESI. A comprehensive evaluation of facet joint pathologies prior to procedure planning is imperative for optimizing treatment outcomes.

## Full-text entities

- **Diseases:** radicular back pain (MESH:D001416), Pain (MESH:D010146), Facet joint degeneration (MESH:D009410)
- **Chemicals:** steroid (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12174188/full.md

---
Source: https://tomesphere.com/paper/PMC12174188