# A case report of delayed persistent third-degree atrioventricular block 7 years after eccentric umbrella occlusion of a perimembranous ventricular septal defect in infancy

**Authors:** Lihui Wei, Decai Zeng, Liuliu Huang, Xiangjie Luo, Ji Wu

PMC · DOI: 10.3389/fped.2025.1591928 · 2025-06-04

## TL;DR

A child who had a heart defect closed with an umbrella device in infancy later developed a serious heart rhythm issue seven years later.

## Contribution

This case highlights the long-term risk of delayed complete heart block following early childhood use of an eccentric umbrella for heart defect closure.

## Key findings

- A child developed third-degree atrioventricular block seven years after an eccentric umbrella occlusion.
- The conduction abnormality persisted despite occluder removal and steroid therapy.
- Long-term ECG monitoring is recommended for high-risk patients with occluders near the conduction system.

## Abstract

This article reports an 8-year-old female patient who underwent trans-thoracic small-incision interventional Pm-VSD occlusion with an eccentric umbrella (defect diameter 10 mm, occluder waist diameter 12 mm) at 4 months of age (July 2017). Seven years after the operation (October 2024), she gradually developed third-degree atrioventricular block. Despite the removal of the occluder and ventricular septal defect repair combined with steroid pulse therapy, the conduction abnormality persisted. This case, with a 7 - year disease course evolution, provides in - depth insights into the development process of delayed complete atrioventricular block (CAVB) following eccentric umbrella occlusion in infancy and early childhood, particularly for high - risk patients with occlusion adjacent to the conduction system. It also suggests the significance of electrocardiogram monitoring for over 5 years post - operation in such high - risk patients.

## Linked entities

- **Diseases:** atrioventricular block (MONDO:0000465), ventricular septal defect (MONDO:0002070)

## Full-text entities

- **Diseases:** VSD (MESH:D004310), CAVB (MESH:D054537), ventricular septal defect (MESH:D006345)
- **Chemicals:** steroid (MESH:D013256)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12174161/full.md

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Source: https://tomesphere.com/paper/PMC12174161