# Carbapenem-resistant Enterobacterales peri-rectal colonization prevalence on admission to two intensive care units in an academic hospital in India

**Authors:** Armaghan-e-Rehman Mansoor, Fabia Edathadathil, Devendhu Suresh, Yathu Krishna, Anu George, Jacaranda van Rheenen, Ige A George, Jennie H Kwon, Emily E Petersen, Matthew Westercamp, Anil Kumar, Sudheer O Vayoth, Margaret A Olsen, Surbhi Leekha, Sanjeev K Singh, David K Warren, Sumanth Gandra

PMC · DOI: 10.1017/ash.2025.10036 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2025-05-30

## TL;DR

A study in India found that 41% of ICU patients were colonized with drug-resistant bacteria upon admission, highlighting the need for better infection control.

## Contribution

The study reports a high prevalence of carbapenem-resistant Enterobacterales in ICU patients in India, with a focus on New Delhi metallo-β-lactamase.

## Key findings

- 41% of ICU patients were colonized with carbapenem-resistant Enterobacterales upon admission.
- New Delhi metallo-β-lactamase was the most common carbapenemase identified.

## Abstract

This study from a South Indian tertiary care hospital found a 41% peri-rectal Carbapenem-resistant Enterobacterales colonization prevalence at intensive care unit admission, with New Delhi metallo-β-lactamase as the predominant carbapenemase. It underscores the need for contextually appropriate, cost-effective infection prevention strategies to mitigate the spread of resistant organisms in Indian healthcare settings.

## Linked entities

- **Species:** Enterobacterales (taxon 91347)

## Full-text entities

- **Diseases:** infection (MESH:D007239)
- **Chemicals:** Carbapenem (MESH:D015780)
- **Species:** Enterobacterales (order) [taxon 91347]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12171904/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12171904/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12171904/full.md

---
Source: https://tomesphere.com/paper/PMC12171904