# Epidemiological trends in autism and other neurodevelopmental disorders in Kazakhstan (2016–2022): a regional and national perspective

**Authors:** Karina Nukeshtayeva, Zhanerke Bolatova, Aza Galayeva, Nurzhamal Shintayeva, Gulmira Zhanalina

PMC · DOI: 10.3389/fpsyt.2025.1520460 · Frontiers in Psychiatry · 2025-06-03

## TL;DR

This study shows a significant rise in autism diagnoses in Kazakhstan from 2016 to 2022, with regional differences and possible links to healthcare and environment.

## Contribution

The study provides the first comprehensive analysis of autism and neurodevelopmental disorder trends in Kazakhstan using national healthcare data.

## Key findings

- Childhood autism diagnoses increased nearly fivefold from 2016 to 2022 (p < 0.01).
- Northern regions of Kazakhstan had higher autism diagnosis rates than southern regions.
- Astana reported a childhood autism prevalence of 263.7 per 100,000 children in 2022.

## Abstract

This study investigates the epidemiological trends of autism spectrum disorder and other neurodevelopmental disorders in Kazakhstan from 2016 to 2022.

Utilizing national healthcare databases, we analyzed the incidence and prevalence of childhood autism, atypical autism, and neurodevelopmental disorders across various regions of Kazakhstan.

Our findings reveal a nearly fivefold increase in the diagnosis of childhood autism and a fourfold increase in atypical autism over the seven-year period, with both trends showing statistical significance (p < 0.01). However, no significant trend was observed for broader neurodevelopmental disorders. Regional disparities were evident, with northern regions showing higher rates of ASD diagnoses compared to the southern regions, likely influenced by factors such as healthcare infrastructure, urbanization, and environmental pollution. Astana showed a marked increase in childhood autism prevalence, reaching 263.7 per 100,000 children by 2022.

Data highlight an important public health trend in Kazakhstan, where the primary incidence of autism spectrum disorders is on the rise, reflecting improved recognition and diagnostic practices.

## Linked entities

- **Diseases:** autism spectrum disorder (MONDO:0005258), atypical autism (MONDO:0016052)

## Full-text entities

- **Diseases:** autism spectrum disorder (MESH:D000067877), neurodevelopmental disorders (MESH:D002658), ASD (MESH:D001321)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12171868/full.md

## References

64 references — full list in the complete paper: https://tomesphere.com/paper/PMC12171868/full.md

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Source: https://tomesphere.com/paper/PMC12171868