# Progressive quadriparesis in a young woman due to a spinal perimedullary arteriovenous fistula (PMAVF type IVa) successfully treated with endovascular therapy: A case report

**Authors:** Fitri Damayanti, Ashari Bahar, Wijoyo Halim

PMC · DOI: 10.1016/j.radcr.2025.05.027 · Radiology Case Reports · 2025-06-03

## TL;DR

A young woman with progressive paralysis was successfully treated for a rare spinal blood vessel abnormality using a minimally invasive procedure.

## Contribution

This case report presents a successful endovascular treatment of a rare PMAVF type IVa with significant functional recovery.

## Key findings

- Transarterial embolization with Onyx successfully occluded the fistula without affecting normal blood flow.
- The patient showed near-complete motor recovery within seven days post-procedure.
- Early diagnosis and endovascular intervention can lead to significant functional improvement in PMAVF cases.

## Abstract

A perimedullary arteriovenous fistula (PMAVF) is a rare spinal vascular malformation that can lead to progressive neurologic deficits. We report a case of a 23-year-old woman presenting with progressive quadriparesis over 6 months. Initial spinal MRI revealed serpiginous flow voids from the cervical to the lumbar region, indicating abnormal vessels. Subsequent spinal angiography confirmed a PMAVF type IVa arising from the anterior radiculomedullary artery at the tenth thoracal (T10) level, shunting directly into a dilated perimedullary venous system. Transarterial embolization using ethylene-vinyl alcohol copolymer (Onyx) successfully occluded the fistula without compromising normal arterial flow. The patient showed marked neurologic recovery, achieving near-complete motor improvement by the seventh day postprocedure. PMAVF is classified as a type IV spinal vascular malformation and may cause severe neurologic symptoms due to venous hypertension, congestion, or hemorrhage. Early diagnosis is crucial, as endovascular embolization offers a minimally invasive treatment option with a favorable safety profile. This case illustrates the importance of timely recognition and intervention in PMAVF, underscoring the potential for significant functional improvement following endovascular therapy.

## Full-text entities

- **Diseases:** congestion (MESH:D002311), fistula (MESH:D005402), spinal vascular malformation (MESH:D054079), PMAVF (MESH:D001164), hemorrhage (MESH:D006470), venous hypertension (MESH:D014647), neurologic deficits (MESH:D009461), quadriparesis (MESH:D011782)
- **Chemicals:** Onyx (MESH:C020320)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12171745/full.md

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Source: https://tomesphere.com/paper/PMC12171745