# Concurrent Diagnosis of Superficial Esophageal Cancer and Esophageal Achalasia: A Case Report and Literature Review

**Authors:** Ai Katsumi, Hideki Mori, Noriko Matsuura, Tatsuhiro Masaoka, Yusaku Takatori, Hideomi Tomida, Teppei Akimoto, Hiroko Ando, Motohiko Kato, Takanori Kanai

PMC · DOI: 10.1002/deo2.70164 · DEN Open · 2025-06-17

## TL;DR

A 70-year-old woman was diagnosed with both esophageal achalasia and superficial esophageal cancer, treated with endoscopic surgery and managed without further invasive procedures.

## Contribution

This case highlights the successful concurrent management of esophageal achalasia and superficial cancer using individualized endoscopic approaches.

## Key findings

- Three superficial lesions were resected en bloc with endoscopic submucosal dissection, showing no lymphovascular invasion.
- Symptoms of achalasia were managed effectively with medication and diet, avoiding peroral endoscopic myotomy.
- The case emphasizes individualized treatment decisions based on symptom severity and lesion characteristics.

## Abstract

We report a case of a 70‐year‐old woman with esophageal achalasia and concurrent superficial esophageal squamous cell carcinoma. Three adjacent superficial lesions were resected en bloc by endoscopic submucosal dissection (ESD), with no lymphovascular invasion. Given that the patient's dysphagia was effectively controlled with medication and dietary modifications, peroral endoscopic myotomy (POEM) was deferred following a careful assessment of the risk–benefit balance. As both ESD and POEM involve submucosal intervention, this case highlights the importance of individualized treatment based on symptom severity and lesion characteristics.

## Linked entities

- **Diseases:** esophageal achalasia (MONDO:0008698), esophageal squamous cell carcinoma (MONDO:0005580)

## Full-text entities

- **Diseases:** esophageal squamous cell carcinoma (MESH:D000077277), Esophageal Achalasia (MESH:D004931), dysphagia (MESH:D003680), Esophageal Cancer (MESH:D004938)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12171625/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12171625/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12171625/full.md

---
Source: https://tomesphere.com/paper/PMC12171625