# Recent Advances in Peripheral Immunoscore in Lung Cancer

**Authors:** Fan XU, Bin LUO, Jianhui TIAN, Yun YANG, Zhenyang CHENG, Youjun LIU

PMC · DOI: 10.3779/j.issn.1009-3419.2025.102.21 · Chinese Journal of Lung Cancer · 2025-05-20

## TL;DR

Peripheral immunoscore is a new tool that helps predict lung cancer outcomes by analyzing immune parameters in the blood.

## Contribution

This paper reviews recent advances in using peripheral immunoscore for lung cancer prediction and clinical applications.

## Key findings

- Peripheral immunoscore can improve early diagnosis and prognosis of lung cancer.
- It helps predict treatment response and adverse reactions in patients.
- The score reflects immune status and tumor microenvironment features.

## Abstract

肺癌是发病率和死亡率最高的恶性肿瘤，肿瘤原发灶-淋巴结-转移（tumor-node metastasis, TNM）分期在肺癌相关预测中逐渐显现局限性，亟待构建新型临床预测模型指导肺癌防治。近年来，外周免疫评分作为一种基于外周免疫相关参数的综合评估体系，在预测模型构建中的价值逐渐凸显。该评分通过量化外周免疫成分的数量及比例，可动态反映机体整体免疫功能状态及肿瘤微环境特征。本文系统总结了外周免疫评分在肺癌早期诊断、用药疗效预测、不良反应预警及预后评估中的最新研究进展，旨在挖掘其潜在的临床应用价值，为开发新型肺癌相关预测模型提供一定的思路与方向。

## Linked entities

- **Diseases:** lung cancer (MONDO:0005138)

## Full-text entities

- **Diseases:** TNM (MESH:D008207), Lung Cancer (MESH:D008175), malignant tumor (MESH:D009369)

## Full text

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## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC12171615/full.md

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Source: https://tomesphere.com/paper/PMC12171615