# First person – Claudia Collier

## TL;DR

This paper explores how persistent neuroinflammation affects colonic motility in a mouse model of Gulf War illness.

## Contribution

The study introduces a new mouse model using pyridostigmine bromide to investigate chronic neuroinflammation and its effects on gut motility.

## Key findings

- Persistent enteric neuroinflammation was shown to chronically impair colonic motility.
- The model uses pyridostigmine bromide to induce Gulf War illness symptoms in mice.
- Findings highlight the role of neuro-immune interactions in gut dysfunction.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping researchers promote themselves alongside their papers. Claudia Collier is first author on ‘
Persistent enteric neuroinflammation chronically impairs colonic motility in a pyridostigmine bromide-induced mouse model of Gulf War illness’, published in BiO. Claudia is a PhD candidate in the lab of Dr Shreya Raghavan at Texas A&M University, College Station, TX, USA, interested in the intersection of using tissue engineering models to investigate neuro-immune interactions.