# First person – Samia Pratt

## TL;DR

This paper discusses a study on gene replacement strategies for treating MTRFR deficiency, a rare mitochondrial disease.

## Contribution

The study evaluates the feasibility of gene replacement as a potential therapeutic approach for MTRFR deficiency.

## Key findings

- Gene replacement strategies were tested for their potential to treat MTRFR deficiency.
- The research provides insights into therapeutic approaches for rare mitochondrial diseases.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Samia Pratt is first author on ‘
Evaluating the feasibility of gene replacement strategies to treat MTRFR deficiency’, published in DMM. Samia is a PhD student in the lab of Robert Burgess at The Jackson Laboratory, Bar Harbor, ME, USA, investigating potential gene therapeutics for rare inherited mitochondrial diseases and peripheral neuropathies.