Author Correction: Identification of stable housekeeping genes for induced pluripotent stem cells and -derived endothelial cells for drug testing

Sheena L. M. Ong; Hans J. Baelde; David G. P. van IJzendoorn; Judith V. M. G. Bovée; Karoly Szuhai

PMC · DOI:10.1038/s41598-025-04721-x·June 16, 2025

Author Correction: Identification of stable housekeeping genes for induced pluripotent stem cells and -derived endothelial cells for drug testing

Sheena L. M. Ong, Hans J. Baelde, David G. P. van IJzendoorn, Judith V. M. G. Bovée, Karoly Szuhai

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Abstract

Linked entities

Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.

Genes2

FOSB PFDN5

Proteins2

Figures3

Click any figure to enlarge with its caption.

Mean Ct values. Mean Ct values of iPSC^WT^, iPSCS^SERPINE1-FOSB^, iPSC-EC^WT^ of each housekeeping gene were shown in a box-and-whisker plot and sorted from the lowest (left) to the highest (right). The five added common housekeeping genes are denoted with an asterisk. The whiskers represent SD of nine samples, three samples per cell line (iPSC^WT^, iPSCS^SERPINE1-FOSB^, and iPSC-EC^WT^).

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TopicsBiomedical Ethics and Regulation · 3D Printing in Biomedical Research · Pluripotent Stem Cells Research

Full text

Correction to: Scientific Reports 10.1038/s41598-022-20435-w, published online 28 September 2022

The original version of this Article contained an error in the gene name PFDN5, which was incorrectly given as PRDN5 in six instances.

As a result, Table 2HKGCOX7A2UBA52HPRT1SLC25A3TMBIM6PRELID1RPL36ALATP5F1CPRDN5

now reads,HKGCOX7A2UBA52HPRT1SLC25A3TMBIM6PRELID1RPL36ALATP5F1CPFDN5

Table 3. GeneDelta-CtBestkeepergeNormNormFinderRefFinderMean SDRankSDRankM valueRankStabilityRankGeomeanComprehensive rankingRPL36AL0.1940.3971.3760.2362.911TMBIM60.25120.3451.2870.1732.912MORF4L20.2160.57141.1880.2584.213HPRT10.2280.3131.1090.2594.764SLC25A30.24110.3142.2610.0915.365GANAB0.34170.85160.77140.52175.696RPN20.29150.54110.89120.2375.927GUSB0.28140.56131.03100.2046.968PRDN50.2050.4291.5440.28116.989

now reads,

Gene Delta-Ct

Bestkeeper

geNorm

NormFinder

RefFinder Mean SDRankSDRankM valueRankStabilityRankGeomeanComprehensive rankingRPL36AL0.1940.3971.3760.2362.911TMBIM60.25120.3451.2870.1732.912MORF4L20.2160.57141.1880.2584.213HPRT10.2280.3131.1090.2594.764SLC25A30.24110.3142.2610.0915.365GANAB0.34170.85160.77140.52175.696RPN20.29150.54110.89120.2375.927GUSB0.28140.56131.03100.2046.968PFDN50.2050.4291.5440.28116.989

In addition, Figures 1, 2, and 3 contained the incorrect gene in their X-axes, and in the Supplementary Information in Table S1. The incorrect files appear below.

Fig. 1. Mean Ct values. Mean Ct values of iPSC^WT^, iPSCS^SERPINE1-FOSB^, iPSC-EC^WT^ of each housekeeping gene were shown in a box-and-whisker plot and sorted from the lowest (left) to the highest (right). The five added common housekeeping genes are denoted with an asterisk. The whiskers represent SD of nine samples, three samples per cell line (iPSC^WT^, iPSCS^SERPINE1-FOSB^, and iPSC-EC^WT^).

Fig. 2geNorm ranking of stability M value. Housekeeping genes are plotted based on their stability M value from the highest (left) to the lowest (right). Black bars are ideal housekeeping genes and grey bars are acceptable housekeeping genes. The five added common housekeeping genes are denoted with an asterisk. Note: this tool is not calculating SD.

Fig. 3NormFinder ranking based on stability value. Housekeeping genes are plotted based on their stability value from the least (left) to the most stable (right). The five added common housekeeping genes are denoted with an asterisk.

The original Article has been corrected.

Supplementary Information

Supplementary Information.