# Acute Cerebrovascular Accident, Renal Failure, and Thrombotic Microangiopathy in a 27‐Year‐Old Male With Malignant Hypertension

**Authors:** Tatiana Gusan, Angelina Hong, Sarah Kaufman, Luis Santiago, Nathan Zaher

PMC · DOI: 10.1002/ccr3.70565 · 2025-06-16

## TL;DR

A 27-year-old man with malignant hypertension developed severe complications like kidney failure and brain issues, emphasizing the risks of high blood pressure.

## Contribution

This case highlights the rare and severe complications of hypertensive emergency in a young adult.

## Key findings

- The patient developed acute cerebrovascular accident and renal failure due to malignant hypertension.
- Thrombotic microangiopathy was also observed as a complication.
- The case underscores the importance of timely management of hypertensive emergencies.

## Abstract

Hypertensive emergency is an acute, significant elevation of blood pressure accompanied by end‐organ damage. We present a case of a 27‐year‐old gentleman who acquired multiple complications of hypertensive emergency, including renal failure and microangiopathy. This highlights the diverse complications of hypertensive emergency and reviews guideline‐based recommendations for management.

## Linked entities

- **Diseases:** hypertensive emergency (MONDO:0006846), malignant hypertension (MONDO:0006846), renal failure (MONDO:0001106), thrombotic microangiopathy (MONDO:0019737), cerebrovascular accident (MONDO:0005098)

## Full-text entities

- **Diseases:** Thrombotic Microangiopathy (MESH:D057049), Renal Failure (MESH:D051437), Cerebrovascular Accident (MESH:D020521), Malignant Hypertension (MESH:D006974), Hypertensive emergency (MESH:D006973), microangiopathy (MESH:D014652), end-organ damage (MESH:C564816)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12170225/full.md

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Source: https://tomesphere.com/paper/PMC12170225