# A Strange Case of Fever: Hematopyometra As the Initial Presentation of Endometrial Adenocarcinoma

**Authors:** Andreia Mandim, Ana Sofia Silva, Rita Moça, Luciana Faria, Fani Ribeiro, Rubina Silva

PMC · DOI: 10.7759/cureus.84278 · 2025-05-17

## TL;DR

A 62-year-old woman with persistent fever and symptoms was found to have a rare uterine condition caused by cancer.

## Contribution

Highlights hematopyometra as an unusual initial sign of endometrial adenocarcinoma in elderly women.

## Key findings

- Hematopyometra was diagnosed as the cause of prolonged fever and systemic symptoms.
- Endometrial adenocarcinoma was identified as the underlying condition.
- Emphasizes considering gynecological issues in elderly patients with unexplained systemic symptoms.

## Abstract

Pyometra is a rare condition involving the accumulation of purulent material within the uterine cavity, typically affecting postmenopausal women. Clinical presentation varies and may be silent, but can include fever, abdominal pain, and vaginal discharge. In this case, we report a 62-year-old woman presenting with prolonged constitutional symptoms and fever, ultimately diagnosed with a large hematopyometra secondary to endometrial adenocarcinoma. This case emphasizes the need to consider gynecological causes in elderly female patients with persistent systemic symptoms.

## Linked entities

- **Diseases:** endometrial adenocarcinoma (MONDO:0005461), pyometra (MONDO:0000497)

## Full-text entities

- **Diseases:** Fever (MESH:D005334), Endometrial Adenocarcinoma (MESH:D016889), abdominal pain (MESH:D015746), Pyometra (MESH:D055112)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12169058/full.md

---
Source: https://tomesphere.com/paper/PMC12169058