# Bronchial Obstruction in Immunoglobulin G4-Related Disease

## TL;DR

This case report describes a 65-year-old man with bronchial obstruction caused by IgG4-related disease, diagnosed through thoracoscopic surgery.

## Contribution

The novelty lies in presenting bronchial obstruction as a rare manifestation of IgG4-related disease in a patient without autoimmune history.

## Key findings

- Bronchial obstruction was identified as a consequence of IgG4-related disease in a 65-year-old man.
- Thoracoscopic segmentectomy confirmed the diagnosis of IgG4-related disease in the patient.

## Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a recently identified systemic fibroinflammatory disorder affecting various organs throughout the body. IgG4-related lung disease is a relatively common manifestation in IgG4-RD and presents with 4 primary pulmonary patterns: nodular, ground-glass opacities, interstitial disease, and peribronchovascular thickening. Peribronchovascular thickening is a frequent pattern in thoracic IgG4-RD involvements. This case report describes bronchial obstruction as a consequence of IgG4-RD in a 65-year-old man with no personal or family history of autoimmune disease. Thoracoscopic segmentectomy was performed, which led to the diagnosis of IgG4-RD.