# Isolated testicular metastasis from prostate cancer following three years of hormone therapy and radiotherapy

## TL;DR

A man with prostate cancer developed a rare testicular metastasis three years after hormone therapy and radiotherapy, which was successfully treated with surgery.

## Contribution

This case highlights the rare occurrence of isolated testicular metastasis from prostate cancer after long-term hormone therapy and radiotherapy.

## Key findings

- Isolated testicular metastasis was identified three years after initial prostate cancer treatment.
- Radical orchiectomy led to undetectable PSA levels and no metastases after one year of follow-up.

## Abstract

This case report presents a 61-year-old male patient diagnosed with high-risk prostate cancer who underwent hormone therapy and radiotherapy. Three years after beginning treatment, rising prostate-specific antigen (PSA) levels led to a PET CT scan, which identified isolated metastases in the left testicle. The patient then underwent a radical orchiectomy. One-year follow up revealed undetectable PSA and no evidence of any metastases. The significance of this case lies in the uncommon occurrence of testicular metastasis from prostate cancer, particularly when presenting in isolation after a prolonged period following hormone therapy and radiotherapy.