# Paraneoplastic Limbic Encephalitis in a Patient With Thymoma

## TL;DR

A young man with thymoma developed limbic encephalitis, a rare brain condition, and improved after radiotherapy.

## Contribution

This case highlights the rare association between thymoma and paraneoplastic limbic encephalitis.

## Key findings

- A patient with thymoma developed paraneoplastic limbic encephalitis after cancer diagnosis and treatment.
- The patient showed clinical improvement following radiotherapy to the primary tumor.

## Abstract

Paraneoplastic limbic encephalitis is a rare neurological disorder that is classically associated with small cell lung cancer, it usually presents with seizures, confusion, behavioral changes and cognitive impairments. It has been associated with a number of onconeural antibodies. Its association with other malignancies is less recognized. We present a case of a young male with a diagnosis of thymoma who developed limbic encephalitis after the diagnosis and the initial treatment of his malignancy. The patient showed clinical improvement after receiving radiotherapy to the primary tumor.