# Comparison of automatic versus constant CPAP in elderly patients after major abdominal surgery: a randomized noninferiority trial

**Authors:** Nguyen Dang Thu, Nguyen Thi Thuy, Le Sau Nguyen, Cong Quyet Thang, Nguyen Ngoc Thach, Nguyen Trung Kien

PMC · DOI: 10.1016/j.bjane.2025.844642 · Brazilian Journal of Anesthesiology · 2025-05-17

## TL;DR

This study compares two types of CPAP in elderly patients after abdominal surgery, finding that constant CPAP improves oxygenation more, while automatic CPAP is more comfortable.

## Contribution

The study provides new evidence on the comparative effectiveness and tolerance of automatic versus constant CPAP in elderly post-surgery patients.

## Key findings

- Constant CPAP improved oxygenation more than automatic CPAP in elderly patients.
- Automatic CPAP was better tolerated, with lower discomfort scores.
- Pulmonary benefits were greater in patients over 70 and those with upper abdominal surgery.

## Abstract

Geriatric patients undergoing major open abdominal surgery are at high risk for postoperative pulmonary complications and hypoxemia. Continuous Positive Airway Pressure (CPAP) after surgery may improve postoperative lung function. This randomized controlled trial compared two CPAP techniques ‒ automatic via nasal mask and constant via facial mask ‒ regarding pulmonary function and patient tolerance.

Sixty patients (≥ 60 years) were randomized (1:1) to receive either automatic CPAP (2–10 cm H2O) via a nasal mask (Group A) or constant CPAP (7.5 cm H2O) via a facial mask (Group C) upon arrival in the post-anesthesia care unit. Oxygenation (PaO2, PaO₂/FiO₂, SpO2) and spirometry (FVC, FEV1, PEF) were assessed preoperatively, postoperatively, and one hour after treatment. Comfort scores (0–10, with 0 indicating the best comfort) and complications were recorded.

PaO₂/FiO2 improvement was lower in Group A (32.6 ± 26.3 mmHg) than in Group C (52.9 ± 40.1 mmHg; p = 0.023). FVC improvement was also lower in Group A (3.7% ± 4.0%) than in Group C (6.7% ± 4.9%; p = 0.012). However, Group A had better tolerance, with lower comfort scores (2 [2–3] vs. 3 [2–4], p = 0.002). Pulmonary function benefits were more pronounced in patients over 70 and those undergoing upper abdominal surgery.

Both CPAP techniques prevent pulmonary decline in geriatric patients post-surgery. While automatic CPAP provides better comfort, constant CPAP improves oxygenation. Although our findings are short-term, they suggest that CPAP mode selection should be tailored based on patient-specific needs.

## Full-text entities

- **Diseases:** pulmonary complications (MESH:D008171), hypoxemia (MESH:D000860), pulmonary decline (MESH:D060825)
- **Chemicals:** PaO₂ (-), H (MESH:D006859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12166376/full.md

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Source: https://tomesphere.com/paper/PMC12166376