# Robot-assisted deep brain stimulation with intraoperative CT imaging and frameless registration module: a new gold-standard?

**Authors:** Gonzague Defrance, Philippe Domenech, Johan Pallud, Marc Zanello

PMC · DOI: 10.1007/s00701-025-06581-w · Acta Neurochirurgica · 2025-06-13

## TL;DR

This paper presents a robot-assisted method for deep brain stimulation that improves accuracy and reduces surgery time compared to traditional techniques.

## Contribution

The paper introduces a new surgical workflow combining a robot, frameless registration, and intraoperative CT for DBS implantation.

## Key findings

- Robot-assisted procedures offer improved accuracy and precision for DBS implantation.
- Intraoperative CT imaging enhances safety and efficiency during surgery.
- The workflow is a reproducible alternative to traditional frame-based methods.

## Abstract

Although stereotactic frame-based techniques remain widely used for deep brain stimulation (DBS) implantation, robot-assisted procedures have demonstrated improved accuracy, enhanced precision, and reduced operative time. Our team has over two decades of experience in robot-assisted surgery and intraoperative imaging.

We detail our current surgical workflow for DBS implantation, combining the Neuromate robot (Renishaw), the NeuroLocate frameless registration module, and intraoperative cone-beam CT imaging using the O-Arm system (Medtronic).

This approach provides a safe, efficient, and reproducible alternative to traditional methods, supporting its broader adoption in modern functional neurosurgery.

The online version contains supplementary material available at 10.1007/s00701-025-06581-w.

## Full-text entities

- **Diseases:** Twiddler's syndrome (MESH:D005359), psychiatric (MESH:D001523), anorexia nervosa (MESH:D000856), epilepsy (MESH:D004827), Dystonia (MESH:D004421), drug-resistant pain (MESH:D000069279), Parkinson Disease (MESH:D010300), movement disorders (MESH:D009069), resistant (MESH:D060467), Essential Tremor (MESH:D020329)
- **Chemicals:** IPG (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12165982/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12165982/full.md

---
Source: https://tomesphere.com/paper/PMC12165982