# Secondary Amyloidosis of the Urinary Bladder Presenting As Urinary Retention

**Authors:** Wyatt MacNevin, Ainsley Bethune, Cheng Wang, Ashley Cox

PMC · DOI: 10.7759/cureus.84096 · Cureus · 2025-05-14

## TL;DR

This paper reports a rare case of bladder amyloidosis causing urinary retention and managed with catheterization.

## Contribution

The novelty lies in presenting a clinical case of secondary bladder amyloidosis with acute urinary retention as the primary symptom.

## Key findings

- Bladder amyloidosis was diagnosed after ruling out malignancy through cystoscopy and pathology.
- The patient failed beta-3 agonist therapy and clean intermittent catheterization before suprapubic catheterization was used.
- The case highlights the importance of considering amyloidosis in patients with unexplained urinary retention.

## Abstract

Bladder amyloidosis is a rare condition of insoluble extracellular protein deposition in the urinary bladder arising as a complication of underlying inflammation and immune dyscrasia. Diagnosis of bladder amyloidosis is done through cystoscopy and evidence of amyloid deposition on pathologic evaluation. Here, we present a case of secondary bladder amyloidosis presenting with acute urinary retention. After ruling out bladder malignancy, the patient was managed with suprapubic catheterization after failing beta-3 agonist therapy and clean intermittent catheterization.

## Full text

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## Figures

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12164731/full.md

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Source: https://tomesphere.com/paper/PMC12164731