# Anti-NMDA Receptor Encephalitis in the Setting of an Immature Ovarian Teratoma: A Case Report and Literature Review

**Authors:** Samantha Metzger, Keely Ulmer, Erik Arneson, Christine Gill, Michael J. Goodheart

PMC · DOI: 10.1155/crog/9923415 · Case Reports in Obstetrics and Gynecology · 2025-06-05

## TL;DR

A 19-year-old woman with anti-NMDA receptor encephalitis caused by an immature ovarian teratoma improved after chemotherapy.

## Contribution

This case report adds to the understanding of anti-NMDAR encephalitis linked to immature ovarian teratomas and their treatment outcomes.

## Key findings

- Chemotherapy led to improvement in the patient despite poor initial condition.
- Published cases of anti-NMDAR encephalitis from immature teratomas were reviewed and summarized.
- The connection between immature ovarian teratomas and anti-NMDAR encephalitis is rare but treatable.

## Abstract

We report a case of a 19-year-old diagnosed with anti-NMDAR encephalitis in relation to an immature ovarian teratoma. Ultimately, chemotherapy resulted in her improvement despite poor performance status. We provide a literature review of the published cases of anti-NMDAR encephalitis caused by immature teratomas and summarize their treatment.

## Linked entities

- **Proteins:** Grin1 (glutamate receptor, ionotropic, NMDA1 (zeta 1))
- **Diseases:** anti-NMDA receptor encephalitis (MONDO:0021081), immature ovarian teratoma (MONDO:0018369)

## Full text

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12163227/full.md

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Source: https://tomesphere.com/paper/PMC12163227