# The mediating role of wellbeing in the relationship between health behaviors and quality of life in people with hepatogenous diabetes

**Authors:** Ying Liang, Shuangqi Li, Lianxin Meng, Xisheng Wang, Zhichuan He, Qingmei Lu, Li Huang, Yijuan Li, Weiping Xie, Hongyun Ji

PMC · DOI: 10.3389/fpubh.2025.1529158 · Frontiers in Public Health · 2025-05-30

## TL;DR

This study shows that wellbeing partially explains how health behaviors affect quality of life in people with hepatogenous diabetes.

## Contribution

The study identifies wellbeing as a partial mediator between health behaviors and quality of life in hepatogenous diabetes patients.

## Key findings

- Health behaviors and wellbeing both positively correlate with quality of life in hepatogenous diabetes patients.
- Wellbeing mediates 44.47% of the effect of health behaviors on quality of life.
- Patients with hepatogenous diabetes show poor quality of life despite generally good health behaviors.

## Abstract

This study aimed to investigate the relationship between health behaviors, wellbeing, and health-related quality of life (HRQoL) in patients with hepatogenous diabetes (HD), with a focus on exploring the mediating effect of the wellbeing index.

A cross-sectional analysis was conducted on 161 people with HD from January to December 2021 at a Grade III, Class A hospital's Department of Gastroenterology in Guangxi Province.

Health behaviors were assessed using the Health-Promoting Lifestyle Profile (HPLP-C), HRQoL was measured with the Chronic Liver Disease Questionnaire (CLDQ), and emotional wellbeing was evaluated using the WHO-5 Wellbeing Index. Correlation analysis and a mediation model were used to explore the relationships between health behaviors, wellbeing, and HRQoL.

The results revealed a significant positive correlation between health behaviors and HRQoL (r = 0.385, p < 0.01) as well as between the wellbeing index and HRQoL (r = 0.513, p < 0.01). The wellbeing index partially mediated the relationship between health behaviors and HRQoL, accounting for 44.47% of the total effect. Despite generally favorable health behaviors, people with HD exhibited poor HRQoL (59.03 ± 17.47), with 28.6% experiencing depressive symptoms.

Improving psychological wellbeing plays a crucial role in enhancing HRQoL among people with HD. Interventions should target both health behaviors and mental health to foster a more positive psychological state and improve overall patient outcomes.

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12162908/full.md

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Source: https://tomesphere.com/paper/PMC12162908