# Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice

**Authors:** Jin Li, Xin Wei, Le Luo

PMC · DOI: 10.3389/fonc.2025.1558946 · Frontiers in Oncology · 2025-05-30

## TL;DR

A rare case of cervical cancer spreading to the liver is reported, highlighting diagnostic challenges and poor prognosis.

## Contribution

This case report adds to the limited literature on rare liver metastasis from cervical adenocarcinoma.

## Key findings

- Liver metastasis from cervical cancer is rare and often misdiagnosed due to atypical imaging features.
- Contrast-enhanced biopsy confirmed the metastatic origin despite initial suspicion of biliary neoplasm.
- The case emphasizes the need for thorough diagnostic evaluation in patients with prior cancer history.

## Abstract

Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient’s surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974), obstructive jaundice (MONDO:0006874)

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC12162578/full.md

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Source: https://tomesphere.com/paper/PMC12162578