# Otogenic Lateral and Transverse Sinovenous Thrombosis in a Child: A Case Report

**Authors:** Astrid Rosero-Castillo, Diana Almendariz-Ramos, Jose Treviño-González

PMC · DOI: 10.7759/cureus.84045 · Cureus · 2025-05-13

## TL;DR

A child with severe ear infection developed rare blood clots in brain veins but fully recovered with timely treatment.

## Contribution

Reports a rare pediatric case of otogenic sinus thrombosis with full recovery following combined treatment.

## Key findings

- A 3-year-old child with AOM developed otogenic lateral and transverse sinovenous thrombosis.
- Treatment with antibiotics, anticoagulation, and tympanostomy tubes led to full recovery.
- Early diagnosis and intervention are critical to prevent fatal outcomes in such cases.

## Abstract

Acute otitis media (AOM) is common in children, but intracranial complications such as meningitis, cerebral abscess, and cerebral venous sinus thrombosis are rare and can be potentially life-threatening. This case describes a three-year-old boy who presented to the emergency room following one week of coryza, fever, cough, malaise, and otalgia, along with three days of severe headache and vomiting. Physical examination revealed hyperemia and bulging of both tympanic membranes on otoscopy, along with an elevated erythrocyte sedimentation rate and elevated levels of leukocytes, C-reactive protein, and D-dimer. Cranial computed tomography scan revealed soft tissue density occupying the mastoid cells bilaterally and enlargement of the right transverse and sigmoid venous sinuses; magnetic resonance imaging of the brain revealed thrombophlebitis in the right internal jugular vein and thrombosis in the transverse and sigmoid sinuses. The diagnosis was bilateral AOM with otogenic lateral right sinus thrombosis, and the patient had also developed bilateral sixth cranial nerve paresis and cerebellitis. He made a full recovery without any sequelae, following treatment that included the placement of tympanostomy tubes in both ears, a 21-day course of systemic antibiotics, and two weeks of anticoagulation therapy with low molecular-weight heparin. Follow-up showed clinical improvement and normalization of inflammatory markers; the radiological images showed complete resolution of thrombosis. Since otogenic lateral sinus thrombosis symptoms can mimic uncomplicated AOM, maintaining a high index of suspicion is essential in preventing fatal outcomes and ensuring favorable recovery in pediatric patients.

## Linked entities

- **Diseases:** acute otitis media (MONDO:0024330), meningitis (MONDO:0021108)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}
- **Diseases:** cough (MESH:D003371), cerebral venous sinus thrombosis (MESH:D012851), AOM (MESH:D010033), Sinovenous Thrombosis (MESH:D013927), vomiting (MESH:D014839), hyperemia (MESH:D006940), inflammatory (MESH:D007249), otogenic lateral sinus thrombosis (MESH:D020227), headache (MESH:D006261), cerebral abscess (MESH:D001922), thrombophlebitis (MESH:D013924), otalgia (MESH:D004433), meningitis (MESH:D008580), coryza (MESH:D003139), fever (MESH:D005334)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12162127/full.md

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Source: https://tomesphere.com/paper/PMC12162127