# Effectiveness of Robot-Assisted Upper Extremity Function Training (Gloreha) on Upper Extremities Function After Stroke: Systematic Review

**Authors:** Chirathip Thawisuk, Sopida Apichai, Waranya Chingchit, Jananya P Dhippayom, Teerapon Dhippayom

PMC · DOI: 10.2196/68268 · JMIR Rehabilitation and Assistive Technologies · 2025-06-05

## TL;DR

This systematic review evaluates the effectiveness of the Gloreha robotic device in improving upper extremity function and daily living activities in stroke patients.

## Contribution

The study provides a comprehensive evaluation of Gloreha's effectiveness in stroke rehabilitation through a systematic review of randomized controlled trials.

## Key findings

- Gloreha training, either combined with or independent of conventional rehabilitation, shows potential in enhancing motor function in stroke survivors.
- Passive Gloreha training combined with conventional rehabilitation improves upper extremity function post-stroke.
- Further research is needed to determine the long-term effects and optimal dosing of Gloreha for ADL improvements.

## Abstract

The Gloreha (Idrogenet SRL) is a robotic device that enhances conventional rehabilitation for improving upper extremity function after stroke, but comprehensive evidence on its effectiveness is still lacking.

The objective of this study was to evaluate the effectiveness of the Gloreha device on upper extremity function and activities of daily living (ADLs) in patients with stroke.

PubMed, Cochrane CENTRAL, CINAHL, Embase, and EBSCO Open Dissertations were searched from January 2013 to January 2024. The inclusion criteria were randomized controlled trials involving adult patients with stroke that compared rehabilitation with the Gloreha device to conventional rehabilitation and reported upper extremity function or ADLs outcomes. All included studies underwent bias risk assessment using the Revised Cochrane risk-of-bias tool for randomized trials.

Out of 1123 studies identified, 3 randomized controlled trials involving 83 participants were included. Of these, 2 trials combined Gloreha training with conventional rehabilitation, while in another trial, patients engaged solely in the training by the Gloreha device. The Gloreha, whether integrated with conventional rehabilitation or used independently, has the potential to enhance motor function and functional ability in survivors of stroke.

Gloreha passive training with conventional rehabilitation improves upper extremity function post stroke, but ADL effects and long-term optimal dosing require further research.

## Linked entities

- **Diseases:** stroke (MONDO:0005098)

## Full-text entities

- **Diseases:** Stroke (MESH:D020521)
- **Chemicals:** Gloreha (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

48 references — full list in the complete paper: https://tomesphere.com/paper/PMC12162109/full.md

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Source: https://tomesphere.com/paper/PMC12162109