# Evaluation of clinical outcomes after partial horizontal laryngectomy

**Authors:** Daniel Abreu Rocha, Gustavo Fernandes de Alvarenga, Daniel Marin Ramos, Leandro Luongo de Matos, Rogerio Aparecido Dedivitis, Marco Aurélio Vamondes Kulcsar, Claudio Roberto Cernea

PMC · DOI: 10.1016/j.bjorl.2025.101614 · Brazilian Journal of Otorhinolaryngology · 2025-05-29

## TL;DR

This study evaluates the effectiveness of partial laryngectomy in preserving laryngeal function and controlling cancer in patients with supraglottic tumors.

## Contribution

The study provides clinical outcomes data on horizontal partial laryngectomy for supraglottic cancer, highlighting its functional and oncological efficacy.

## Key findings

- 86.4% of patients did not experience cancer recurrence after the procedure.
- 62.2% of patients were decannulated by the end of treatment.
- HPL showed adequate local control and survival rates compared to total laryngectomy.

## Abstract

•Supracricoid horizontal laryngectomy provides a high rate of deccanulation and swallowing.•It was commonest surgical procedure up to T3 supraglottic cancer.•14% of patients required total laryngectomy for poor functional status.

Supracricoid horizontal laryngectomy provides a high rate of deccanulation and swallowing.

It was commonest surgical procedure up to T3 supraglottic cancer.

14% of patients required total laryngectomy for poor functional status.

Evaluate the oncological and functional outcomes of patients submitted to HPL for the treatment of LSCC.

A retrospective descriptive study of patients submitted to HPL, performed at a cancer referral center, between January 2011 and December 2017.

We evaluated 37 patients. The major pathological staging of the primary tumor was pT3 (35.1%), followed by pT2 (32.4%). Five patients required adjuvant radiotherapy; 62.2% of the patients were decannulated by the end of the treatment; 10.8% weren’t decannulated; 8.1% underwent a retracheostomy, and 18.9% had total laryngectomy. From the patients submitted to total laryngectomy, 3 cases were due to rehabilitation failure, 2 due to recurrence and 2 cases due to postoperative suture dehiscence. About 89% of the patients resumed oral feeding following the procedure; 86.4% didn’t present disease recurrence; 31 patients survived without disease; 3 died from disease-related causes, and 3 from unrelated causes.

HPL is an alternative procedure to total laryngectomy, presenting adequate rates of local control and overall survival while also maintaining laryngeal function. The main challenge to HPL remains achieving an ideal selection of patients.

Level IV.

## Linked entities

- **Diseases:** supraglottic cancer (MONDO:0004357)

## Full-text entities

- **Diseases:** cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12161998/full.md

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Source: https://tomesphere.com/paper/PMC12161998