# Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

**Authors:** Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol

PMC · DOI: 10.1002/1878-0261.70004 · Molecular Oncology · 2025-02-21

## TL;DR

This paper discusses how involving patients in cancer research and healthcare decisions can improve outcomes and ensure studies meet patient needs.

## Contribution

The paper highlights inclusive frameworks and initiatives to overcome barriers in patient engagement, especially for marginalized groups.

## Key findings

- Patient engagement fosters better treatment outcomes and research relevance.
- Barriers like power imbalances and socioeconomic disparities hinder meaningful patient involvement.
- Inclusive partnerships and trust are essential for impactful patient-centered research.

## Abstract

Patient engagement in healthcare and research empowers patients to actively participate in decision‐making, treatment planning, and research design, fostering better treatment outcomes and relevance. However, barriers, such as power imbalances, structural limitations, a lack of awareness, and socioeconomic disparities, often hinder meaningful involvement, particularly for marginalized groups. Overcoming these challenges requires inclusive frameworks and infrastructures to promote collaboration among patients, researchers, and other stakeholders. Initiatives like the Patient Engagement Open Forum or World Cancer Research Day underscore the importance of patient‐centered approaches. By fostering trust, transparency, and shared decision‐making, a more inclusive and impactful healthcare and research ecosystem can be achieved.

Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals. Despite progress, barriers like unequal access and lack of awareness remain. Overcoming these challenges requires inclusive partnerships, diverse representation, and a shared commitment to patient‐centered care and research.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** Cancer (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12161468/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12161468/full.md

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Source: https://tomesphere.com/paper/PMC12161468