# Genome sequence and methylome profile of Natrinema pallidum strain NMX15-1, a halophilic archaeon, from Permian Period halite, Carlsbad, New Mexico

**Authors:** Aram Khoshnaw, Beatriz Toledo Akiti, Tamas Vincze, Priya DasSarma, Alexey Fomenkov, Dennis W. Powers, Richard J. Roberts, Shiladitya DasSarma

PMC · DOI: 10.1128/mra.01287-24 · Microbiology Resource Announcements · 2025-05-20

## TL;DR

This paper presents the genome and methylome of a 250-million-year-old halophilic archaeon from New Mexico.

## Contribution

The study provides the first genome sequence of Natrinema pallidum from ancient Permian halite.

## Key findings

- The genome is 3.8 Mbp and includes a chromosome and three plasmids.
- The proteome is highly acidic with 3,784 proteins identified.

## Abstract

We report the 3.8-Mbp genome sequence of an extreme Haloarchaeon, Natrinema pallidum strain NMX15-1, isolated from 250-million-year-old halite samples of the Permian Period. PacBio’s long-read sequencing revealed a genome comprising a chromosome (3.5-Mbp) and three plasmids (203, 71, and 56-Kbp). The proteome is highly acidic and includes 3,784 proteins.

## Linked entities

- **Species:** Natrinema pallidum (taxon 69527)

## Full-text entities

- **Species:** Natrinema pallidum (species) [taxon 69527]

## Full text

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## References

25 references — full list in the complete paper: https://tomesphere.com/paper/PMC12160562/full.md

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Source: https://tomesphere.com/paper/PMC12160562