# Nextclade data set for the ORF5-based lineage classification of PRRSV-1

**Authors:** Michael Zeller, Jennifer Chang, Giovani Trevisan, Phillip C. Gauger, Jianqiang Zhang

PMC · DOI: 10.1128/mra.00303-25 · Microbiology Resource Announcements · 2025-05-27

## TL;DR

This paper introduces a standardized data set for classifying PRRSV-1 using ORF5, enabling faster and more consistent analysis.

## Contribution

The novel contribution is a global nomenclature-based Nextclade dataset for PRRSV-1 lineage classification.

## Key findings

- The dataset allows rapid sequence analysis and comparison with reference strains.
- It promotes broader adoption of standardized classification for PRRSV-1 research and surveillance.

## Abstract

A Nextclade data set for PRRSV-1 ORF5 based on a global nomenclature for standardized lineage classification was developed. This tool enables rapid sequence analysis, visualization, and comparison with reference strains and vaccines. By providing accessibility, it facilitates broader adoption of PRRSV-1 classification frameworks for research and surveillance.

## Linked entities

- **Genes:** CWC15 (CWC15 spliceosome associated protein) [NCBI Gene 51503]

## Full-text entities

- **Genes:** CWC15 (CWC15 spliceosome associated protein) [NCBI Gene 51503] {aka AD002, C11orf5, Cwf15, HSPC148, ORF5}
- **Species:** porcine reproductive and respiratory syndrome virus 1 (no rank) [taxon 1965066]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12160553/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12160553/full.md

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Source: https://tomesphere.com/paper/PMC12160553