# A complete circular genome of ΦX174 host Escherichia coli C122

**Authors:** Victoria A. Sharp, Siobain Duffy

PMC · DOI: 10.1128/mra.00061-25 · Microbiology Resource Announcements · 2025-04-29

## TL;DR

This paper presents the complete circular genome of E. coli C122, a host for the bacteriophage ΦX174, showing it is a distinct strain.

## Contribution

The paper provides a new complete genome sequence of E. coli C122, highlighting its ~1% genetic difference from another published version.

## Key findings

- The genome of E. coli C122 is circular and complete.
- It is approximately 1% different from another published E. coli C122 genome.
- This justifies its classification as a distinct strain.

## Abstract

Escherichia coli C122 and the bacteriophage that uses it as the standard laboratory host (ΦX174) make up a dream team of model microorganisms. This ΦX174 host is the second complete, published genome of E. coli C122, and is ~1% different from the other, justifying that it is another strain.

## Full-text entities

- **Species:** Escherichia coli (E. coli, species) [taxon 562], Bacteriophage sp. (species) [taxon 38018]
- **Cell lines:** C122 — Homo sapiens (Human), Transformed cell line (CVCL_F345), PhiX174 — Homo sapiens (Human), Rhabdomyosarcoma, Cancer cell line (CVCL_U955)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12160529/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12160529/full.md

---
Source: https://tomesphere.com/paper/PMC12160529