# Transcriptome sequencing data sets of Escherichia coli K-12 MG1655 treated with novobiocin, tetracycline, and rifampicin

## TL;DR

This study provides gene expression data from E. coli treated with antibiotics to better understand bacterial resistance mechanisms.

## Contribution

The novelty lies in identifying gene clusters responding to specific antibiotic treatments in E. coli.

## Key findings

- Gene clusters responding to RNA synthesis inhibition were identified.
- Genes reacting to protein synthesis inhibition were detected.
- Genes affected by DNA gyrase inhibition were found.

## Abstract

This report presents transcriptome datasets for Escherichia coli MG1655 treated with novobiocin, rifampicin, and tetracycline. Clusters of genes that respond to inhibition of RNA synthesis, protein synthesis, and DNA gyrase activity have been identified. The data may help to understand the mechanisms of general and specific resistance in E. coli.