# methylMapR—an R package to generate the functional prokaryotic methylome

## TL;DR

methylMapR is an R package that helps analyze prokaryotic methylomes using PacBio sequencing data for three bacterial species.

## Contribution

The novel contribution is the development of methylMapR for functional methylome analysis in prokaryotes.

## Key findings

- methylMapR enables functional methylome analysis from PacBio sequencing data.
- The package was applied to Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa.
- Comparative analyses revealed insights into prokaryotic methylation patterns.

## Abstract

Here, we present an R package called methylMapR to capture the functional methylome from long read sequencing of prokaryotic genomes using the PacBio sequencing platform. We then describe its utility by comparative analyses of the functional methylomes in three bacterial species—Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa.