# Complete genome sequence of Prevotella histicola T05-04

**Authors:** Kelyah Spurgeon, John R. Erb-Downward, Gary B. Huffnagle, Ariangela J. Kozik

PMC · DOI: 10.1128/mra.00144-25 · Microbiology Resource Announcements · 2025-04-29

## TL;DR

This paper presents the complete genome sequence of Prevotella histicola T05-04, a bacterium linked to human oral cancer.

## Contribution

The novelty is the closed genome assembly of P. histicola T05-04 using Nanopore sequencing.

## Key findings

- The genome was previously fragmented into 109 contigs.
- Nanopore sequencing enabled the assembly of a complete, closed genome.
- This provides a more accurate reference for future studies on this bacterium.

## Abstract

Prevotella histicola is a non-spore forming, obligatory anaerobic, gram-negative coccobacillus bacterium originally isolated from human oral squamous cell carcinoma tissue. Previously, the available genome for P. histicola T05-04 consisted of 109 contigs. Here, we report the complete (closed) genome sequence for Prevotella histicola T05-04 assembled using Nanopore sequencing.

## Linked entities

- **Diseases:** oral squamous cell carcinoma (MONDO:0004958)
- **Species:** Prevotella histicola (taxon 470565)

## Full-text entities

- **Diseases:** oral squamous cell carcinoma (MESH:D000077195)
- **Species:** Homo sapiens (human, species) [taxon 9606], Prevotella histicola (species) [taxon 470565]

## Full text

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12160458/full.md

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Source: https://tomesphere.com/paper/PMC12160458