# Complete genome sequence of Helicobacter pylori isolated from residents in southwestern Colombia using Oxford Nanopore sequencing technology

## TL;DR

This paper reports the full genome sequences of Helicobacter pylori from Colombian patients, using new sequencing technology to study its potential link to gastric cancer.

## Contribution

The study provides complete genome sequences of H. pylori strains from Colombia and identifies mobilizable plasmids with MOBP-type relaxases.

## Key findings

- Genome sequences of H. pylori from Colombian patients were assembled using Nanopore sequencing.
- Some strains contained mobilizable plasmids with MOBP-type relaxases.
- Virulence genes in H. pylori may explain its association with gastric cancer.

## Abstract

Genome sequences of Helicobacter pylori strains isolated from patients in Nariño, Colombia, with gastric lesions were assembled using Nanopore sequencing. Plasmids were detected in some strains and were predicted to be mobilizable, with relaxases of the MOBP type. H. pylori’s virulence genes may explain the link with gastric cancer.